IHL · Vitamins & actives
D-Panthenol
- INCI name
- Panthenol
- CAS number
- 81-13-0
- EC number
- 201-327-3
- Physical form
- Liquid
- Country of origin
- Germany · Switzerland · China
- HS code
- 2936.24
- Grade
- Cosmetic / USP available
- Shelf life
- 24–36 months
INCI note
D-panthenol (dexpanthenol) is the biologically active isomer. DL-panthenol is the racemic mixture and is sold as a crystalline powder. Both are stocked; they are not interchangeable at the same use level.
The biologically active isomer at full strength. Half the market sells 50% or 75% dilutions under the same name — check what you are actually paying for.
| Appearance | Clear viscous liquid, colorless to pale yellow |
|---|---|
| Odour | Odorless |
| Solubility | Water solubility >509 g/L at 22 °C. Readily soluble in methanol and ethanol. Insoluble in oils and fats. |
| Melting point | Freezing point −25 °C · Bp 235.6 °C (decomposes) |
| pH | 9.0–10.5 at 5% aqueous — strongly alkaline. This will shift your batch pH and it matters above about 2%. |
| HLB | n/a |
| Storage | Avoid heat and direct sunlight. Keep tightly closed and dry. |
| Manufacturing process | Synthetic — from D-pantolactone and 3-aminopropanol. |
Certifications
- Gluten-free
- Non-GMO
- Palm-free
- Vegan
In full: Vegan · Gluten-free · Palm-free · Non-GMO (synthetic)
| Application | Use rate |
|---|---|
| Shampoo | 0.5–2% |
| Conditioner | 1–3% |
| Lotion | 1–3% |
| Cream | 1–5% |
| Serum | 1–5% |
Formulation notes
- pH 9–10.5 at 5%. Above about 2% in your formula this will move your finished pH and you need to adjust after addition, not before.
- Hydrolyzes at pH extremes. Most stable around pH 4–7 and it does not enjoy prolonged heat — add at cool-down.
- Panthenol converts to pantothenic acid on skin. That is the mechanism and it is well established. It is not a hair-growth agent and we will not sell it as one.
Applications
- Shampoo and conditioner
- Leave-in treatment
- Lotion and cream
- Serum
- Lip balm
- After-sun
Not classified as hazardous
Not a hazardous substance or mixture. Confirmed against the DSM manufacturer SDS, an authoritative primary source.
- Transport classification
- Not regulated as a dangerous good under UN, DOT, IATA or IMDG.
- Allergen statement
- No FDA major food allergen. Synthetic — no GMO concern, no soy, no gluten.
California Proposition 65
No listed constituent identified.
- SDS Safety Data Sheet On request
- TDS Technical Data Sheet On request
- COA Certificate of Analysis On request
- Allergen Allergen statement On request
- GMO GMO statement On request
- BSE/TSE BSE/TSE statement On request
- Vegan Vegan statement On request
- RSPO RSPO certificate On request
We send documents on request. No account, no vendor-qualification fee. Ask for D-Panthenol documents.